And those who dispute (polytheists, etc. with Our Messenger Muhammad SAW) as regards Our Ayat (proofs, signs, verses, etc. of Islamic Monotheism) may know that there is no place of refuge for them (from Allahs punishment)
So that those who argue about Our signs can know that they have no place of escape.
Al-muntakhab fi tafsir al-Qur'an al-Karim
A matter of fact to be apprehended by the minds of those who contend with opposing arguments against Our signs, and seem resolved to dispute the truth of Our revelations, that there is no escape nor can they go unpunished